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Vita Sana Medical Center

Prolotherapy · Scottsdale, Arizona

Prolotherapy for Knee Pain

Knees are prolotherapy's home turf: most chronic knee pain involves lax ligaments — MCL, LCL, or the joint capsule — that let the joint shift and grind. Dr. Luca Lioce, NMD at Vita Sana Medical Center in Scottsdale treats the knee's full ligament network with prolotherapy, often adding PRP for the joint surface and A2M therapy to protect cartilage.

Dr. Luca Lioce, NMD — Vita Sana Medical Center, Scottsdale

Dr. Luca Lioce, NMD

Founder & Medical Director, Vita Sana Medical Center · Clinical Peptide Society member · 10+ years of clinical experience · Scottsdale, AZ

Knee problems that respond well

  • Chronic knee pain with "giving way" or looseness
  • MCL/LCL sprains that never fully healed
  • Early-to-moderate osteoarthritis with instability
  • Patellar tracking and tendon pain
  • Post-injury knees not ready (or right) for surgery

Why stabilize before anything else

A loose knee wears its cartilage unevenly — no injection into the joint space can outrun that mechanical problem. By tightening the stabilizing ligaments first, prolotherapy addresses why the knee keeps degrading; PRP and A2M then have a stable joint to heal. This sequencing is central to how Dr. Lioce treats knees.

Frequently Asked Questions

Can prolotherapy help bone-on-bone knees?

Advanced arthritis responds less; early-to-moderate cases with instability respond best. An honest exam tells you which category your knee is in.

How many sessions for a knee?

Typically three to six, spaced about a month apart, adjusted by your response.

Who does knee prolotherapy in Scottsdale?

Dr. Luca Lioce, NMD at Vita Sana Medical Center — (480) 579-5290, 4300 N. Miller Rd., Suite 144.

Prolotherapy Treatments at Vita Sana Medical Center

Explore the full Prolotherapy Treatments service — or book a consultation with Scottsdale’s leading regenerative medicine expert.

Vita Sana Medical Center · 4300 N. Miller Rd. Suite 144, Scottsdale, AZ 85251 · (480) 579-5290 · Serving Scottsdale, Paradise Valley, Phoenix, Tempe, Mesa & Fountain Hills. Individual results vary; treatment requires medical evaluation.