Prolotherapy · Scottsdale, Arizona
How Does Prolotherapy Work?
Prolotherapy works by converting a chronic, stalled injury back into an acute, healing one — on purpose and under control. Each injection of mild dextrose solution at a ligament attachment triggers about a week of local inflammation, followed by weeks of collagen deposition that thickens and tightens the structure. Session by session, the joint regains the stability that stops the pain cycle.
Founder & Medical Director, Vita Sana Medical Center · Clinical Peptide Society member · 10+ years of clinical experience · Scottsdale, AZ
Your treatment, session by session
Session 1: Dr. Luca Lioce, NMD examines the joint, maps lax attachments, and treats the full network — often 10–20 precise micro-injections in minutes. Days 1–3: expected achiness as the healing response begins. Weeks 1–4: collagen builds; many patients notice early stability. Sessions 2–6: each round strengthens further, spaced 3–4 weeks apart, with progress checked against the original exam.
What determines success
- Accurate diagnosis — instability vs. other causes of pain
- Complete treatment of the ligament network
- Adequate spacing and session count
- Not blunting the response with NSAIDs during healing
- Progressive loading between sessions
Frequently Asked Questions
How fast does prolotherapy work?
Some stability improvement is often felt within the first month, with full benefit building across the treatment series and for weeks after the final session.
Can I take painkillers after prolotherapy?
Acetaminophen is fine; anti-inflammatories are avoided around sessions because the controlled inflammation is the mechanism.
Does prolotherapy work for everyone?
It works best when instability is the true pain driver — which is exactly what the initial exam establishes before you commit to a series.
Prolotherapy Treatments at Vita Sana Medical Center
Explore the full Prolotherapy Treatments service — or book a consultation with Scottsdale’s leading regenerative medicine expert.
Vita Sana Medical Center · 4300 N. Miller Rd. Suite 144, Scottsdale, AZ 85251 · (480) 579-5290 · Serving Scottsdale, Paradise Valley, Phoenix, Tempe, Mesa & Fountain Hills. Individual results vary; treatment requires medical evaluation.